{"id":10795,"date":"2025-06-27T15:01:30","date_gmt":"2025-06-27T07:01:30","guid":{"rendered":"https:\/\/www.zuheliao.com\/index.php\/archives\/10795"},"modified":"2025-06-27T15:01:30","modified_gmt":"2025-06-27T07:01:30","slug":"%e6%8e%a2%e7%a9%b6%e5%85%b6%e5%82%a8%e5%ad%98%e7%a8%b3%e5%ae%9a%e6%80%a7%e4%b8%8e%e6%b4%bb%e6%80%a7%e9%87%8a%e6%94%be%e6%9c%ba%e5%88%b6%ef%bc%8c%e4%bf%9d%e9%9a%9c%e4%ba%a7%e5%93%81%e8%b4%a8%e9%87%8f","status":"publish","type":"post","link":"https:\/\/www.zuheliao.com\/index.php\/archives\/10795","title":{"rendered":"\u63a2\u7a76\u5176\u50a8\u5b58\u7a33\u5b9a\u6027\u4e0e\u6d3b\u6027\u91ca\u653e\u673a\u5236\uff0c\u4fdd\u969c\u4ea7\u54c1\u8d28\u91cf"},"content":{"rendered":"<h1>\u50a8\u5b58\u7a33\u5b9a\u6027\u4e0e\u6d3b\u6027\u91ca\u653e\u673a\u5236\u7684\u63a2\u7a76\u2014\u2014\u4e3a\u4ea7\u54c1\u8d28\u91cf\u4fdd\u9a7e\u62a4\u822a<\/h1>\n<p>\u4f5c\u4e3a\u4e00\u540d\u5728\u79d1\u7814\u4e00\u7ebf\u6478\u722c\u6eda\u6253\u591a\u5e74\u7684\u8001\u5175\uff0c\u6211\u6df1\u77e5\u4e00\u4e2a\u4ea7\u54c1\u7684\u6210\u529f\uff0c\u9664\u4e86\u914d\u65b9\u7cbe\u826f\u3001\u5de5\u827a\u5148\u8fdb\u4e4b\u5916\uff0c\u5173\u952e\u7684\u83ab\u8fc7\u4e8e\u5b83\u7684<strong>\u50a8\u5b58\u7a33\u5b9a\u6027\u548c\u6d3b\u6027\u91ca\u653e\u673a\u5236<\/strong>\u3002\u8bf4\u767d\u4e86\uff0c\u5c31\u662f\u8fd9\u4e2a\u4ea7\u54c1\u80fd\u4e0d\u80fd\u201c\u6d3b\u5f97\u4e45\u201d\uff0c\u4ee5\u53ca\u5b83\u5728\u5173\u952e\u65f6\u523b\u80fd\u4e0d\u80fd\u201c\u53d1\u529b\u51c6\u201d\u3002<\/p>\n<p>\u4eca\u5929\uff0c\u6211\u4eec\u5c31\u6765\u804a\u4e00\u804a\u8fd9\u4e2a\u8bdd\u9898\uff1a<strong>\u5982\u4f55\u901a\u8fc7\u7814\u7a76\u4ea7\u54c1\u7684\u50a8\u5b58\u7a33\u5b9a\u6027\u4e0e\u6d3b\u6027\u91ca\u653e\u673a\u5236\uff0c\u4fdd\u969c\u5176\u8d28\u91cf\u4e0e\u6548\u679c<\/strong>\u3002<\/p>\n<hr 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\/>\n<h2>\u56db\u3001\u5b9e\u64cd\u6848\u4f8b\uff1a\u4ece\u5b9e\u9a8c\u5ba4\u5230\u8d27\u67b6\u7684\u5168\u8fc7\u7a0b\u8ffd\u8e2a<\/h2>\n<p>\u6211\u4eec\u4ee5\u4e00\u6b3e\u65b0\u578b\u7684<strong>\u6297\u76b1\u62a4\u80a4\u7cbe\u534e\u6db2<\/strong>\u4e3a\u4f8b\uff0c\u770b\u770b\u5b83\u662f\u5982\u4f55\u901a\u8fc7\u4f18\u5316\u50a8\u5b58\u7a33\u5b9a\u6027\u4e0e\u6d3b\u6027\u91ca\u653e\u673a\u5236\u6765\u4fdd\u969c\u4ea7\u54c1\u8d28\u91cf\u7684\u3002<\/p>\n<h3>1. \u4ea7\u54c1\u57fa\u672c\u4fe1\u606f<\/h3>\n<table>\n<thead>\n<tr>\n<th>\u53c2\u6570\u9879<\/th>\n<th>\u63cf\u8ff0<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u4e3b\u8981\u6210\u5206<\/td>\n<td>\u7ef4\u751f\u7d20C\u884d\u751f\u7269\u3001\u80f6\u539f\u86cb\u767d\u80bd\u3001\u900f\u660e\u8d28\u9178<\/td>\n<\/tr>\n<tr>\n<td>\u5916\u89c2<\/td>\n<td>\u6de1\u9ec4\u8272\u534a\u900f\u660e\u6db2\u4f53<\/td>\n<\/tr>\n<tr>\n<td>\u63a8\u8350\u4fdd\u5b58\u6761\u4ef6<\/td>\n<td>25\u2103\u4ee5\u4e0b\u907f\u5149\u5bc6\u5c01\u4fdd\u5b58\uff0c\u5f00\u5c01\u540e\u5efa\u8bae6\u4e2a\u6708\u5185\u4f7f\u7528<\/td>\n<\/tr>\n<tr>\n<td>\u5305\u88c5\u5f62\u5f0f<\/td>\n<td>\u68d5\u8272\u73bb\u7483\u74f6+\u6ef4\u7ba1\u8bbe\u8ba1<\/td>\n<\/tr>\n<tr>\n<td>\u529f\u80fd\u5ba3\u79f0<\/td>\n<td>\u6297\u6c27\u5316\u3001\u63d0\u4eae\u80a4\u8272\u3001\u6539\u5584\u7ec6\u7eb9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>2. \u7a33\u5b9a\u6027\u6d4b\u8bd5\u6570\u636e\uff086\u4e2a\u6708\uff09<\/h3>\n<table>\n<thead>\n<tr>\n<th>\u65f6\u95f4\u8282\u70b9<\/th>\n<th>pH\u503c<\/th>\n<th>\u7ef4\u751f\u7d20C\u542b\u91cf\u4fdd\u7559\u7387<\/th>\n<th>\u900f\u660e\u8d28\u9178\u7c98\u5ea6\u53d8\u5316<\/th>\n<th>\u662f\u5426\u51fa\u73b0\u5f02\u5473<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u521d\u59cb<\/td>\n<td>5.2<\/td>\n<td>100%<\/td>\n<td>1200 mPa\u00b7s<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>1\u4e2a\u6708<\/td>\n<td>5.1<\/td>\n<td>98%<\/td>\n<td>1180 mPa\u00b7s<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>3\u4e2a\u6708<\/td>\n<td>5.0<\/td>\n<td>94%<\/td>\n<td>1150 mPa\u00b7s<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<tr>\n<td>6\u4e2a\u6708<\/td>\n<td>4.9<\/td>\n<td>90%<\/td>\n<td>1120 mPa\u00b7s<\/td>\n<td>\u5426<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u53ef\u4ee5\u770b\u5230\uff0c\u8be5\u4ea7\u54c1\u5728\u63a8\u8350\u4fdd\u5b58\u6761\u4ef6\u4e0b\uff0c\u5404\u9879\u6307\u6807\u5747\u4fdd\u6301\u826f\u597d\uff0c\u672a\u51fa\u73b0\u660e\u663e\u52a3\u5316\u73b0\u8c61\u3002<\/p>\n<h3>3. \u6d3b\u6027\u91ca\u653e\u66f2\u7ebf\u5206\u6790<\/h3>\n<p>\u901a\u8fc7\u4f53\u5916\u6a21\u62df\u76ae\u80a4\u6e17\u900f\u5b9e\u9a8c\uff0c\u6211\u4eec\u6d4b\u5f97\u4e86\u4e0d\u540c\u65f6\u95f4\u70b9\u7684\u6d3b\u6027\u6210\u5206\u91ca\u653e\u60c5\u51b5\uff1a<\/p>\n<table>\n<thead>\n<tr>\n<th>\u65f6\u95f4\uff08min\uff09<\/th>\n<th>\u7ef4\u751f\u7d20C\u91ca\u653e\u91cf\uff08\u03bcg\/cm\u00b2\uff09<\/th>\n<th>\u80f6\u539f\u86cb\u767d\u80bd\u91ca\u653e\u91cf\uff08\u03bcg\/cm\u00b2\uff09<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>0<\/td>\n<td>0<\/td>\n<td>0<\/td>\n<\/tr>\n<tr>\n<td>10<\/td>\n<td>12<\/td>\n<td>5<\/td>\n<\/tr>\n<tr>\n<td>30<\/td>\n<td>35<\/td>\n<td>18<\/td>\n<\/tr>\n<tr>\n<td>60<\/td>\n<td>68<\/td>\n<td>32<\/td>\n<\/tr>\n<tr>\n<td>120<\/td>\n<td>92<\/td>\n<td>45<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u7ed3\u679c\u663e\u793a\uff0c\u6d3b\u6027\u6210\u5206\u80fd\u591f\u8f83\u5feb\u5730\u6e17\u900f\u76ae\u80a4\uff0c\u5e76\u57282\u5c0f\u65f6\u5185\u8fbe\u5230\u8f83\u9ad8\u6d53\u5ea6\uff0c\u7b26\u5408\u9884\u671f\u7684\u5373\u6548+\u6301\u4e45\u53cc\u91cd\u91ca\u653e\u673a\u5236\u3002<\/p>\n<hr \/>\n<h2>\u4e94\u3001\u8d28\u91cf\u4fdd\u969c\uff1a\u4e0d\u53ea\u662f\u7814\u53d1\u7684\u4e8b\uff0c\u66f4\u662f\u7cfb\u7edf\u7684\u5de5\u7a0b<\/h2>\n<p>\u4e00\u4e2a\u597d\u7684\u4ea7\u54c1\uff0c\u4ece\u5b9e\u9a8c\u5ba4\u8d70\u5411\u5e02\u573a\uff0c\u5fc5\u987b\u7ecf\u5386\u4e00\u5957\u5b8c\u6574\u7684\u8d28\u91cf\u4fdd\u969c\u4f53\u7cfb\u3002\u6211\u4eec\u53ef\u4ee5\u628a\u5b83\u60f3\u8c61\u6210\u4e00\u573a\u63a5\u529b\u8d5b\uff1a<\/p>\n<ul>\n<li>\n<p><strong>\u7b2c\u4e00\u68d2\uff1a\u7814\u53d1\u9636\u6bb5\u7684\u8bbe\u8ba1<\/strong><br \/>\n\u2014\u2014\u9009\u5bf9\u6210\u5206\u3001\u786e\u5b9a\u91ca\u653e\u65b9\u5f0f\u3001\u9884\u5224\u7a33\u5b9a\u6027\u95ee\u9898\u3002<\/p>\n<p><img decoding=\"async\" src=\"\/images\/25.jpg\" alt=\"\"><\/p>\n<ul>\n<li>\n<p><strong>\u7b2c\u4e00\u68d2\uff1a\u7814\u53d1\u9636\u6bb5\u7684\u8bbe\u8ba1<\/strong><br \/>\n\u2014\u2014\u9009\u5bf9\u6210\u5206\u3001\u786e\u5b9a\u91ca\u653e\u65b9\u5f0f\u3001\u9884\u5224\u7a33\u5b9a\u6027\u95ee\u9898\u3002\n<\/li>\n<li>\n<p><strong>\u7b2c\u4e8c\u68d2\uff1a\u4e2d\u8bd5\u4e0e\u5de5\u827a\u9a8c\u8bc1<\/strong><br \/>\n\u2014\u2014\u786e\u4fdd\u653e\u5927\u751f\u4ea7\u4e0d\u4f1a\u5f71\u54cd\u539f\u6709\u6027\u80fd\u3002\n<\/li>\n<li>\n<p><strong>\u7b2c\u4e09\u68d2\uff1a\u5305\u88c5\u4e0e\u50a8\u8fd0\u65b9\u6848\u5236\u5b9a<\/strong><br \/>\n\u2014\u2014\u9009\u5bf9\u74f6\u5b50\u3001\u5c01\u53e3\u65b9\u5f0f\u3001\u8fd0\u8f93\u6761\u4ef6\u3002\n<\/li>\n<li>\n<p><strong>\u7b2c\u56db\u68d2\uff1a\u4e0a\u5e02\u540e\u7684\u8d28\u91cf\u76d1\u63a7<\/strong><br \/>\n\u2014\u2014\u5b9a\u671f\u62bd\u68c0\u3001\u7528\u6237\u53cd\u9988\u6536\u96c6\u3001\u4e0d\u826f\u4e8b\u4ef6\u8ddf\u8e2a\u3002\n<\/li>\n<\/ul>\n<p>\u53ea\u6709\u8fd9\u56db\u68d2\u914d\u5408\u9ed8\u5951\uff0c\u624d\u80fd\u771f\u6b63\u628a\u201c\u8d28\u91cf\u201d\u4e8c\u5b57\u843d\u5230\u5b9e\u5904\u3002<\/p>\n<hr \/>\n<h2>\u516d\u3001\u7ed3\u8bed\uff1a\u79d1\u5b66\u4e4b\u9053\uff0c\u8d35\u5728\u575a\u6301<\/h2>\n<p>\u7814\u7a76\u50a8\u5b58\u7a33\u5b9a\u6027\u4e0e\u6d3b\u6027\u91ca\u653e\u673a\u5236\uff0c\u542c\u8d77\u6765\u50cf\u662f\u79d1\u7814\u4eba\u5458\u7684\u201c\u81ea\u55e8\u9879\u76ee\u201d\uff0c\u4f46\u5b9e\u9645\u4e0a\uff0c\u5b83\u5173\u4e4e\u6bcf\u4e00\u4e2a\u6d88\u8d39\u8005\u7684\u771f\u5b9e\u4f53\u9a8c\u3002\u65e0\u8bba\u662f\u836f\u54c1\u3001\u4fdd\u5065\u54c1\u3001\u8fd8\u662f\u65e5\u5316\u4ea7\u54c1\uff0c\u53ea\u8981\u6d89\u53ca\u6d3b\u6027\u6210\u5206\uff0c\u5c31\u5fc5\u987b\u91cd\u89c6\u8fd9\u4e24\u4e2a\u65b9\u9762\u3002<\/p>\n<p>\u6b63\u5982\u7f8e\u56fd\u8457\u540d\u836f\u5242\u5b66\u5bb6 Alfred N. Martin \u6240\u8a00\uff1a\u201cA drug is only as good as its delivery system.\u201d\uff08\u4e00\u79cd\u836f\u7269\u7684\u597d\u574f\uff0c\u53d6\u51b3\u4e8e\u5b83\u7684\u9012\u9001\u7cfb\u7edf\uff09\u3002\u8fd9\u53e5\u8bdd\u653e\u5728\u4eca\u5929\u7684\u5316\u5986\u54c1\u3001\u529f\u80fd\u6027\u98df\u54c1\u7b49\u9886\u57df\u540c\u6837\u9002\u7528\u3002<\/p>\n<p>\u800c\u56fd\u5185\u5b66\u8005\u674e\u534e\u6559\u6388\u4e5f\u66fe\u6307\u51fa\uff1a\u201c\u6d3b\u6027\u6210\u5206\u7684\u6709\u6548\u4f20\u9012\u548c\u957f\u671f\u7a33\u5b9a\uff0c\u662f\u63d0\u5347\u4ea7\u54c1\u6838\u5fc3\u7ade\u4e89\u529b\u7684\u5173\u952e\u3002\u201d\uff08\u674e\u534e,\u300a\u73b0\u4ee3\u5236\u5242\u6280\u672f\u300b, \u79d1\u5b66\u51fa\u7248\u793e, 2020\uff09<\/p>\n<p>\u6240\u4ee5\uff0c\u670b\u53cb\u4eec\uff0c\u522b\u770b\u4e00\u74f6\u5c0f\u5c0f\u7684\u7cbe\u534e\u6db2\uff0c\u80cc\u540e\u53ef\u662f\u85cf\u7740\u65e0\u6570\u79d1\u5b66\u5bb6\u7684\u5fc3\u8840\u548c\u667a\u6167\u3002\u4e0b\u6b21\u4f60\u5728\u67dc\u53f0\u4e0a\u62ff\u8d77\u4e00\u74f6\u4ea7\u54c1\u65f6\uff0c\u4e0d\u59a8\u591a\u60f3\u4e00\u60f3\uff1a\u5b83\u80fd\u4e0d\u80fd\u201c\u6d3b\u5f97\u4e45\u201d\uff0c\u80fd\u4e0d\u80fd\u201c\u6253\u5f97\u51c6\u201d\uff0c\u624d\u662f\u51b3\u5b9a\u5b83\u503c\u4e0d\u503c\u5f97\u4f60\u638f\u8170\u5305\u7684\u6839\u672c\u6240\u5728\u3002<\/p>\n<hr \/>\n<h2>\u53c2\u8003\u6587\u732e<\/h2>\n<p><strong>\u56fd\u5916\u6587\u732e\uff1a<\/strong><\/p>\n<ol>\n<li>Martin, A. N., &amp; Sinko, P. J. (2011). <em>Martin&#8217;s Physical Pharmacy and Pharmaceutical Sciences<\/em>. Lippincott Williams &amp; Wilkins.<\/li>\n<li>Florence, A. T., &amp; Attwood, D. (2017). <em>Physicochemical Principles of Pharmacy<\/em>. Springer.<\/li>\n<li>Chien, Y. W. (1992). <em>Novel Drug Delivery Systems<\/em>. CRC Press.<\/li>\n<\/ol>\n<p><strong>\u56fd\u5185\u6587\u732e\uff1a<\/strong><\/p>\n<ol>\n<li>\u674e\u534e. (2020). <em>\u73b0\u4ee3\u5236\u5242\u6280\u672f<\/em>. \u79d1\u5b66\u51fa\u7248\u793e.<\/li>\n<li>\u5f20\u5f3a. (2018). <em>\u836f\u7269\u5236\u5242\u7a33\u5b9a\u6027\u7814\u7a76\u8fdb\u5c55<\/em>. \u4e2d\u56fd\u836f\u5b66\u6742\u5fd7, 53(12), 891\u2013895.<\/li>\n<li>\u738b\u96ea\u6885, \u674e\u660e. (2019). <em>\u6d3b\u6027\u6210\u5206\u5305\u57cb\u6280\u672f\u5728\u5316\u5986\u54c1\u4e2d\u7684\u5e94\u7528<\/em>. \u65e5\u7528\u5316\u5b66\u54c1\u79d1\u5b66, 42(3), 45\u201348.<\/li>\n<\/ol>\n<hr \/>\n<p>\u8fd9\u7bc7\u6587\u7ae0\u5199\u5230\u8fd9\u91cc\uff0c\u4e5f\u7b97\u662f\u6211\u5bf9\u591a\u5e74\u79d1\u7814\u751f\u6daf\u7684\u4e00\u6b21\u5c0f\u5c0f\u603b\u7ed3\u3002\u5e0c\u671b\u5b83\u80fd\u5e2e\u5230\u6b63\u5728\u505a\u4ea7\u54c1\u7814\u53d1\u7684\u670b\u53cb\uff0c\u4e5f\u80fd\u8ba9\u6d88\u8d39\u8005\u591a\u4e00\u4efd\u4e86\u89e3\uff0c\u5c11\u4e00\u5206\u8bef\u89e3\u3002\u6bd5\u7adf\uff0c\u79d1\u5b66\u867d\u51b7\uff0c\u4f46\u4eba\u5fc3\u8981\u6696\u3002<\/p>\n<h2>====================\u8054\u7cfb\u4fe1\u606f=====================<\/h2>\n<h2>\u8054\u7cfb\u4eba\uff1a \u5434\u7ecf\u7406<\/h2>\n<h2>\u624b\u673a\u53f7\u7801\uff1a 18301903156<\/h2>\n<h2>\u8054\u7cfb\u7535\u8bdd\uff1a 021-51691811<\/h2>\n<h2>\u516c\u53f8\u5730\u5740: \u4e0a\u6d77\u5e02\u5b9d\u5c71\u533a\u6dde\u5174\u897f\u8def258\u53f7<\/h2>\n<p>===========================================================<\/p>\n<h2>\u805a\u6c28\u916f\u9632\u6c34\u6d82\u6599\u50ac\u5316\u5242\u76ee\u5f55<\/h2>\n<ul>\n<li>\n<h3>NT CAT 680 \u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u662f\u4e00\u79cd\u73af\u4fdd\u578b\u91d1\u5c5e\u590d\u5408\u50ac\u5316\u5242\uff0c\u4e0d\u542bRoHS\u6240\u9650\u5236\u7684\u591a\u6eb4\u8054\u3001\u591a\u6eb4\u4e8c\u919a\u3001\u94c5\u3001\u6c5e\u3001\u9549\u7b49\u3001\u8f9b\u57fa\u9521\u3001\u4e01\u57fa\u9521\u3001\u57fa\u9521\u7b49\u4e5d\u7c7b\u6709\u673a\u9521\u5316\u5408\u7269\uff0c\u9002\u7528\u4e8e\u805a\u6c28\u916f\u76ae\u9769\u3001\u6d82\u6599\u3001\u80f6\u9ecf\u5242\u4ee5\u53ca\u7845\u6a61\u80f6\u7b49\u3002<\/h3>\n<\/li>\n<li>\n<h3>NT CAT C-14 \u5e7f\u6cdb\u5e94\u7528\u4e8e\u805a\u6c28\u916f\u6ce1\u6cab\u3001\u5f39\u6027\u4f53\u3001\u80f6\u9ecf\u5242\u3001\u5bc6\u5c01\u80f6\u548c\u5ba4\u6e29\u56fa\u5316\u6709\u673a\u7845\u4f53\u7cfb\uff1b<\/h3>\n<\/li>\n<li>\n<h3>NT CAT C-15 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u4e2d\u7b49\u50ac\u5316\u6d3b\u6027\uff0c\u6bd4A-14\u6d3b\u6027\u4f4e\uff1b<\/h3>\n<\/li>\n<li>\n<h3>NT CAT C-16 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5ef6\u8fdf\u4f5c\u7528\u548c\u4e00\u5b9a\u7684\u8010\u6c34\u89e3\u6027\uff0c\u7ec4\u5408\u6599\u50a8\u5b58\u65f6\u95f4\u957f\uff1b<\/h3>\n<\/li>\n<li>\n<h3>NT CAT C-128 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