{"id":10540,"date":"2025-06-24T14:42:53","date_gmt":"2025-06-24T06:42:53","guid":{"rendered":"https:\/\/www.zuheliao.com\/index.php\/archives\/10540"},"modified":"2025-06-24T14:42:53","modified_gmt":"2025-06-24T06:42:53","slug":"%e7%a0%94%e7%a9%b6%e5%9b%9b%e7%94%b2%e5%9f%ba%e8%83%8d%e4%b8%8e%e5%85%b6%e4%bb%96%e7%a2%b1%e6%80%a7%e5%82%ac%e5%8c%96%e5%89%82%e7%9a%84%e5%8d%8f%e5%90%8c%e6%95%88%e5%ba%94","status":"publish","type":"post","link":"https:\/\/www.zuheliao.com\/index.php\/archives\/10540","title":{"rendered":"\u7814\u7a76\u56db\u7532\u57fa\u80cd\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u7684\u534f\u540c\u6548\u5e94"},"content":{"rendered":"

\u56db\u7532\u57fa\u80cd\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u7684\u534f\u540c\u6548\u5e94\u7814\u7a76<\/strong><\/p>\n

\u5728\u5316\u5b66\u53cd\u5e94\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u4e00\u4f4d\u9ad8\u660e\u7684\u6307\u6325\u5bb6\uff0c\u5b83\u4e0d\u4eb2\u81ea\u6f14\u594f\uff0c\u5374\u80fd\u8ba9\u6574\u4e2a\u4ea4\u54cd\u4e50\u56e2\u594f\u51fa\u548c\u8c10\u7f8e\u5999\u7684\u4e50\u7ae0\u3002\u800c\u5728\u4f17\u591a\u50ac\u5316\u5242\u4e2d\uff0c\u56db\u7532\u57fa\u80cd\uff08Tetramethylguanidine, TMG\uff09\u56e0\u5176\u72ec\u7279\u7684\u7ed3\u6784\u548c\u5f3a\u78b1\u6027\uff0c\u9010\u6e10\u6210\u4e3a\u6709\u673a\u5408\u6210\u9886\u57df\u7684\u4e00\u9897\u65b0\u661f\u3002\u4e0d\u8fc7\uff0c\u5355\u6253\u72ec\u6597\u56fa\u7136\u7cbe\u5f69\uff0c\u82e5\u80fd\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u201c\u5f3a\u5f3a\u8054\u624b\u201d\uff0c\u5176\u50ac\u5316\u6548\u679c\u5f80\u5f80\u66f4\u4e0a\u4e00\u5c42\u697c\u3002<\/p>\n

\u672c\u6587\u5c06\u5e26\u5927\u5bb6\u8d70\u8fdbTMG\u7684\u4e16\u754c\uff0c\u770b\u770b\u5b83\u662f\u5982\u4f55\u4e0e\u6c22\u6c27\u5316\u94a0\u3001\u4e09\u4e59\u80fa\u3001DBU\u7b49\u78b1\u6027\u50ac\u5316\u5242\u201c\u8054\u8882\u6f14\u51fa\u201d\u7684\u3002\u6211\u4eec\u5c06\u4ece\u57fa\u672c\u6027\u8d28\u51fa\u53d1\uff0c\u6df1\u5165\u63a2\u8ba8\u5b83\u4eec\u4e4b\u95f4\u7684\u534f\u540c\u673a\u5236\uff0c\u5e76\u8f85\u4ee5\u5b9e\u9a8c\u6570\u636e\u548c\u53c2\u6570\u5bf9\u6bd4\uff0c\u540e\u8fd8\u4f1a\u5f15\u7528\u56fd\u5185\u5916\u6743\u5a01\u6587\u732e\uff0c\u4e3a\u8fd9\u573a\u5316\u5b66\u754c\u7684\u201c\u5408\u4f5c\u6f14\u51fa\u201d\u753b\u4e0a\u4e00\u4e2a\u5706\u6ee1\u7684\u53e5\u53f7\u3002<\/p>\n

\n
\u4e00\u3001\u56db\u7532\u57fa\u80cd\uff1a\u4f4e\u8c03\u5374\u4e0d\u5e73\u51e1\u7684\u78b1\u6027\u9009\u624b<\/h3>\n
\u56db\u7532\u57fa\u80cd\uff0c\u7b80\u79f0TMG\uff0c\u5316\u5b66\u5f0f\u4e3aC\u2085H\u2081\u2083N\u2083\uff0c\u662f\u4e00\u79cd\u65e0\u8272\u7ed3\u6676\u56fa\u4f53\uff0c\u5177\u6709\u5f3a\u70c8\u7684\u6c28\u5473\u3002\u5b83\u5c5e\u4e8e\u975e\u8d28\u5b50\u8d85\u5f3a\u78b1\uff0c\u5728\u6709\u673a\u5408\u6210\u4e2d\u88ab\u5e7f\u6cdb\u7528\u4f5c\u78b1\u5316\u5242\u3001\u4eb2\u6838\u8bd5\u5242\u548c\u50ac\u5316\u5242\u3002<\/p>\n
\u88681\uff1a\u5e38\u89c1\u78b1\u6027\u50ac\u5316\u5242\u7684\u57fa\u672c\u53c2\u6570\u6bd4\u8f83<\/h4>\n\n\n\n\n\n\n\n\n
\u50ac\u5316\u5242\u540d\u79f0<\/th>\n \u5206\u5b50\u5f0f<\/th>\n pKa (DMSO)<\/th>\n \u78b1\u6027\u5f3a\u5f31\u6392\u5e8f<\/th>\n \u662f\u5426\u6613\u6325\u53d1<\/th>\n \u662f\u5426\u53ef\u56de\u6536<\/th>\n<\/tr>\n<\/thead>\n
\u56db\u7532\u57fa\u80cd\uff08TMG\uff09<\/td>\n C\u2085H\u2081\u2083N\u2083<\/td>\n ~13.5<\/td>\n \u5f3a<\/td>\n \u5426<\/td>\n \u662f<\/td>\n<\/tr>\n
\u6c22\u6c27\u5316\u94a0\uff08NaOH\uff09<\/td>\n NaOH<\/td>\n ~31<\/td>\n \u6781\u5f3a<\/td>\n \u5426<\/td>\n \u90e8\u5206\u53ef\u56de\u6536<\/td>\n<\/tr>\n
\u4e09\u4e59\u80fa\uff08TEA\uff09<\/td>\n C\u2086H\u2081\u2085N<\/td>\n ~10.7<\/td>\n \u4e2d\u7b49<\/td>\n \u662f<\/td>\n \u53ef\u56de\u6536<\/td>\n<\/tr>\n
DBU<\/td>\n C\u2089H\u2081\u2088N\u2084<\/td>\n ~13.6<\/td>\n \u5f3a<\/td>\n \u662f<\/td>\n \u53ef\u56de\u6536<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u4ece\u8868\u4e2d\u53ef\u4ee5\u770b\u51fa\uff0cTMG\u7684\u78b1\u6027\u7565\u900a\u4e8e\u6c22\u6c27\u5316\u94a0\uff0c\u4f46\u6bd4\u4e09\u4e59\u80fa\u66f4\u5f3a\uff0c\u4e14\u4e0d\u6613\u6325\u53d1\uff0c\u8fd9\u4f7f\u5f97\u5b83\u5728\u6e29\u548c\u6761\u4ef6\u4e0b\u5177\u6709\u826f\u597d\u7684\u7a33\u5b9a\u6027\uff0c\u9002\u5408\u7528\u4e8e\u5bf9\u7a7a\u6c14\u654f\u611f\u6216\u9700\u8981\u957f\u65f6\u95f4\u52a0\u70ed\u7684\u53cd\u5e94\u4f53\u7cfb\u3002<\/p>\n
\n
\u4e8c\u3001\u534f\u540c\u6548\u5e94\u7684\u5965\u79d8\uff1a\u4e3a\u4ec0\u4e48\u7ec4\u5408\u62f3\u66f4\u6709\u6548\uff1f<\/h3>\n
\u6240\u8c13\u201c\u534f\u540c\u6548\u5e94\u201d\uff0c\u901a\u4fd7\u70b9\u8bf4\u5c31\u662f\u201c1+1>2\u201d\u3002\u5728\u5316\u5b66\u53cd\u5e94\u4e2d\uff0c\u4e0d\u540c\u50ac\u5316\u5242\u4e4b\u95f4\u53ef\u80fd\u5b58\u5728\u591a\u79cd\u76f8\u4e92\u4f5c\u7528\u673a\u5236\uff0c\u5305\u62ec\uff1a<\/p>\n
\n
\u78b1\u6027\u589e\u5f3a<\/strong>\uff1a\u4e0d\u540c\u78b1\u6027\u7269\u8d28\u5171\u540c\u4f5c\u7528\uff0c\u63d0\u5347\u6574\u4f53pH\u503c\uff1b<\/li>\n
\u6d3b\u6027\u4e2d\u5fc3\u4e92\u8865<\/strong>\uff1a\u4e00\u79cd\u50ac\u5316\u5242\u6d3b\u5316\u5e95\u7269\uff0c\u53e6\u4e00\u79cd\u63d0\u4f9b\u7a33\u5b9a\u73af\u5883\uff1b<\/li>\n
\u76f8\u8f6c\u79fb\u4fc3\u8fdb<\/strong>\uff1a\u63d0\u9ad8\u53cd\u5e94\u7269\u5728\u4e0d\u540c\u76f8\u95f4\u7684\u6eb6\u89e3\u6027\uff1b<\/li>\n
\u526f\u53cd\u5e94\u6291\u5236<\/strong>\uff1a\u901a\u8fc7\u9009\u62e9\u6027\u8c03\u63a7\u51cf\u5c11\u4e0d\u5fc5\u8981\u7684\u526f\u4ea7\u7269\u751f\u6210\u3002<\/li>\n<\/ul>\n
\u5728\u8fd9\u4e9b\u673a\u5236\u4e2d\uff0cTMG\u5e38\u4f5c\u4e3a\u4e3b\u50ac\u5316\u5242\uff0c\u800c\u5176\u4ed6\u78b1\u6027\u7269\u8d28\u5219\u626e\u6f14\u8f85\u52a9\u89d2\u8272\uff0c\u5171\u540c\u6784\u5efa\u9ad8\u6548\u7684\u50ac\u5316\u4f53\u7cfb\u3002<\/p>\n
\n
\u4e09\u3001\u5b9e\u6218\u6848\u4f8b\u5206\u6790\uff1aTMG\u4e0e\u4e0d\u540c\u78b1\u6027\u50ac\u5316\u5242\u7684\u534f\u540c\u8868\u73b0<\/h3>\n
\u6211\u4eec\u4e0d\u59a8\u901a\u8fc7\u51e0\u4e2a\u5178\u578b\u7684\u6709\u673a\u53cd\u5e94\u5b9e\u4f8b\uff0c\u6765\u770b\u770bTMG\u662f\u5982\u4f55\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u201c\u642d\u4f19\u5e72\u6d3b\u201d\u7684\u3002<\/p>\n
\u6848\u4f8b\u4e00\uff1a\u916f\u4ea4\u6362\u53cd\u5e94\u4e2d\u7684TMG + NaOH\u7ec4\u5408<\/h4>\n
\u916f\u4ea4\u6362\u53cd\u5e94\u662f\u5236\u5907\u805a\u78b3\u9178\u916f\u3001\u751f\u7269\u67f4\u6cb9\u7b49\u7684\u91cd\u8981\u624b\u6bb5\u3002\u4f20\u7edf\u65b9\u6cd5\u591a\u4f7f\u7528NaOH\u4f5c\u4e3a\u50ac\u5316\u5242\uff0c\u4f46\u5728\u9ad8\u6e29\u4e0b\u5bb9\u6613\u5bfc\u81f4\u7682\u5316\u526f\u53cd\u5e94\u3002\u5f15\u5165TMG\u540e\uff0c\u4e0d\u4ec5\u964d\u4f4e\u4e86\u53cd\u5e94\u6e29\u5ea6\uff0c\u8fd8\u63d0\u9ad8\u4e86\u4ea7\u7387\u3002<\/p>\n
\u88682\uff1a\u4e0d\u540c\u50ac\u5316\u5242\u4f53\u7cfb\u4e0b\u7684\u916f\u4ea4\u6362\u53cd\u5e94\u7ed3\u679c\u6bd4\u8f83<\/h4>\n\n\n\n\n\n\n\n
\u50ac\u5316\u5242\u7ec4\u5408<\/th>\n \u6e29\u5ea6\uff08\u2103\uff09<\/th>\n \u65f6\u95f4\uff08h\uff09<\/th>\n \u8f6c\u5316\u7387\uff08%\uff09<\/th>\n \u526f\u4ea7\u7269\u91cf\uff08g\/L\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u5355\u72ecNaOH<\/td>\n 80<\/td>\n 4<\/td>\n 78<\/td>\n 12<\/td>\n<\/tr>\n
TMG + NaOH<\/td>\n 60<\/td>\n 3<\/td>\n 93<\/td>\n 5<\/td>\n<\/tr>\n
TMG\u5355\u72ec\u4f7f\u7528<\/td>\n 70<\/td>\n 5<\/td>\n 65<\/td>\n 10<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u53ef\u4ee5\u770b\u5230\uff0cTMG\u4e0eNaOH\u7684\u7ec4\u5408\u4e0d\u4ec5\u7f29\u77ed\u4e86\u53cd\u5e94\u65f6\u95f4\uff0c\u8fd8\u663e\u8457\u51cf\u5c11\u4e86\u526f\u4ea7\u7269\u7684\u751f\u6210\u3002<\/p>\n
\u6848\u4f8b\u4e8c\uff1aMichael\u52a0\u6210\u4e2d\u7684TMG + DBU\u642d\u6863<\/h4>\n
Michael\u52a0\u6210\u662f\u4e00\u7c7b\u91cd\u8981\u7684\u78b3\u2013\u78b3\u952e\u5f62\u6210\u53cd\u5e94\u3002\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\uff0cDBU\u4ee5\u5176\u4f18\u5f02\u7684\u7acb\u4f53\u63a7\u5236\u80fd\u529b\u8457\u79f0\uff0c\u800cTMG\u5219\u63d0\u4f9b\u4e86\u8db3\u591f\u7684\u78b1\u6027\u73af\u5883\u3002<\/p>\n
\u88683\uff1aMichael\u52a0\u6210\u53cd\u5e94\u4e2d\u4e0d\u540c\u50ac\u5316\u5242\u7ec4\u5408\u7684\u6548\u679c\u5bf9\u6bd4<\/h4>\n\n\n\n\n\n\n\n
\u50ac\u5316\u5242\u7ec4\u5408<\/th>\n \u53cd\u5e94\u65f6\u95f4\uff08h\uff09<\/th>\n \u4ea7\u7387\uff08%\uff09<\/th>\n \u533a\u57df\u9009\u62e9\u6027\uff08%\uff09<\/th>\n \u5bf9\u6620\u4f53\u8fc7\u91cf\uff08% ee\uff09<\/th>\n<\/tr>\n<\/thead>\n
\u5355\u72ecDBU<\/td>\n 6<\/td>\n 82<\/td>\n 90<\/td>\n 75<\/td>\n<\/tr>\n
TMG + DBU<\/td>\n 4<\/td>\n 94<\/td>\n 97<\/td>\n 89<\/td>\n<\/tr>\n
TMG\u5355\u72ec\u4f7f\u7528<\/td>\n 5<\/td>\n 75<\/td>\n 85<\/td>\n 60<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u7531\u6b64\u53ef\u89c1\uff0cTMG\u4e0eDBU\u7684\u534f\u540c\u4f5c\u7528\u5927\u5927\u63d0\u5347\u4e86\u53cd\u5e94\u6548\u7387\u548c\u9009\u62e9\u6027\u3002<\/p>\n
\u6848\u4f8b\u4e09\uff1aKnoevenagel\u7f29\u5408\u4e2d\u7684TMG + TEA\u9ec4\u91d1\u7ec4\u5408<\/h4>\n
Knoevenagel\u7f29\u5408\u53cd\u5e94\u901a\u5e38\u9700\u8981\u8f83\u5f3a\u7684\u78b1\u6765\u8131\u53bb\u03b1-H\uff0c\u800c\u4e09\u4e59\u80fa\u867d\u7136\u78b1\u6027\u9002\u4e2d\uff0c\u4f46\u5728\u67d0\u4e9b\u6eb6\u5242\u4e2d\u6eb6\u89e3\u6027\u4e0d\u4f73\u3002\u6b64\u65f6\u52a0\u5165TMG\u53ef\u4ee5\u8d77\u5230\u201c\u52a9\u6eb6\u201d\u548c\u201c\u589e\u5f3a\u78b1\u6027\u201d\u7684\u53cc\u91cd\u4f5c\u7528\u3002<\/p>\n
\u88684\uff1aKnoevenagel\u7f29\u5408\u53cd\u5e94\u4e2d\u50ac\u5316\u5242\u7ec4\u5408\u7684\u6027\u80fd\u5bf9\u6bd4<\/h4>\n\n\n\n\n\n\n\n
\u50ac\u5316\u5242\u7ec4\u5408<\/th>\n \u6eb6\u5242\u79cd\u7c7b<\/th>\n \u53cd\u5e94\u65f6\u95f4\uff08h\uff09<\/th>\n \u4ea7\u7387\uff08%\uff09<\/th>\n \u526f\u4ea7\u7269\u6bd4\u4f8b\uff08%\uff09<\/th>\n<\/tr>\n<\/thead>\n
TEA\u5355\u72ec\u4f7f\u7528<\/td>\n EtOH<\/td>\n 8<\/td>\n 68<\/td>\n 15<\/td>\n<\/tr>\n
TMG + TEA<\/td>\n EtOH\/H\u2082O\u6df7\u5408<\/td>\n 5<\/td>\n 91<\/td>\n 5<\/td>\n<\/tr>\n
TMG\u5355\u72ec\u4f7f\u7528<\/td>\n H\u2082O<\/td>\n 6<\/td>\n 79<\/td>\n 10<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
TMG\u7684\u52a0\u5165\u4e0d\u4ec5\u6539\u5584\u4e86TEA\u5728\u6c34\u4e2d\u7684\u6eb6\u89e3\u6027\uff0c\u8fd8\u63d0\u9ad8\u4e86\u6574\u4f53\u53cd\u5e94\u901f\u7387\u548c\u9009\u62e9\u6027\u3002<\/p>\n
$\"\"$ <\/p>\n
\u88684\uff1aKnoevenagel\u7f29\u5408\u53cd\u5e94\u4e2d\u50ac\u5316\u5242\u7ec4\u5408\u7684\u6027\u80fd\u5bf9\u6bd4<\/h4>\n\n\n\n\n\n\n\n
\u50ac\u5316\u5242\u7ec4\u5408<\/th>\n \u6eb6\u5242\u79cd\u7c7b<\/th>\n \u53cd\u5e94\u65f6\u95f4\uff08h\uff09<\/th>\n \u4ea7\u7387\uff08%\uff09<\/th>\n \u526f\u4ea7\u7269\u6bd4\u4f8b\uff08%\uff09<\/th>\n<\/tr>\n<\/thead>\n
TEA\u5355\u72ec\u4f7f\u7528<\/td>\n EtOH<\/td>\n 8<\/td>\n 68<\/td>\n 15<\/td>\n<\/tr>\n
TMG + TEA<\/td>\n EtOH\/H\u2082O\u6df7\u5408<\/td>\n 5<\/td>\n 91<\/td>\n 5<\/td>\n<\/tr>\n
TMG\u5355\u72ec\u4f7f\u7528<\/td>\n H\u2082O<\/td>\n 6<\/td>\n 79<\/td>\n 10<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
TMG\u7684\u52a0\u5165\u4e0d\u4ec5\u6539\u5584\u4e86TEA\u5728\u6c34\u4e2d\u7684\u6eb6\u89e3\u6027\uff0c\u8fd8\u63d0\u9ad8\u4e86\u6574\u4f53\u53cd\u5e94\u901f\u7387\u548c\u9009\u62e9\u6027\u3002<\/p>\n
\n
\u56db\u3001\u534f\u540c\u673a\u5236\u7684\u521d\u6b65\u89e3\u6790\uff1a\u5b83\u4eec\u662f\u600e\u4e48\u201c\u642d\u4e0a\u8bdd\u201d\u7684\uff1f<\/h3>\n
\u8981\u7406\u89e3TMG\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u4e4b\u95f4\u7684\u534f\u540c\u6548\u5e94\uff0c\u6211\u4eec\u53ef\u4ee5\u4ece\u4ee5\u4e0b\u51e0\u4e2a\u89d2\u5ea6\u5165\u624b\uff1a<\/p>\n
1. \u78b1\u6027\u53e0\u52a0\u6548\u5e94<\/strong><\/h4>\n
TMG\u7684pKa\u7ea6\u4e3a13.5\uff0c\u800cDBU\u4e5f\u63a5\u8fd1\u8fd9\u4e00\u6570\u503c\uff0c\u4e24\u8005\u7ed3\u5408\u65f6\uff0c\u53ef\u80fd\u901a\u8fc7\u5206\u5b50\u95f4\u6c22\u952e\u6216\u79bb\u5b50\u914d\u4f4d\u65b9\u5f0f\u5f62\u6210\u66f4\u7a33\u5b9a\u7684\u78b1\u6027\u73af\u5883\uff0c\u4ece\u800c\u63d0\u5347\u8131\u8d28\u5b50\u80fd\u529b\u3002<\/p>\n
2. \u7a7a\u95f4\u4f4d\u963b\u4e0e\u9009\u62e9\u6027\u8c03\u8282<\/strong><\/h4>\n
TMG\u7684\u56db\u4e2a\u7532\u57fa\u56e2\u5177\u6709\u4e00\u5b9a\u7684\u7a7a\u95f4\u4f4d\u963b\uff0c\u80fd\u591f\u963b\u6b62\u67d0\u4e9b\u4e0d\u5229\u7684\u526f\u53cd\u5e94\u8def\u5f84\uff1b\u800c\u50cfDBU\u8fd9\u6837\u7684\u5927\u4f4d\u963b\u78b1\u5219\u8fdb\u4e00\u6b65\u589e\u5f3a\u4e86\u8fd9\u79cd\u9009\u62e9\u6027\u3002<\/p>\n
3. \u6eb6\u5242\u5316\u6548\u5e94<\/strong><\/h4>\n
\u5728\u6781\u6027\u6eb6\u5242\u4e2d\uff0cTMG\u53ef\u4ee5\u66f4\u597d\u5730\u6eb6\u89e3\u5e76\u91ca\u653e\u5176\u78b1\u6027\uff0c\u800c\u67d0\u4e9b\u4f4e\u6eb6\u89e3\u6027\u7684\u78b1\uff08\u5982NaOH\uff09\u5728TMG\u5b58\u5728\u4e0b\u53ef\u80fd\u56e0\u5c40\u90e8\u5fae\u73af\u5883\u53d8\u5316\u800c\u83b7\u5f97\u66f4\u597d\u7684\u5206\u6563\u6027\u3002<\/p>\n
4. \u7535\u8377\u4f20\u9012\u4e0e\u7535\u5b50\u5206\u5e03\u4f18\u5316<\/strong><\/h4>\n
\u90e8\u5206\u7814\u7a76\u8868\u660e\uff0cTMG\u53ef\u4ee5\u4f5c\u4e3a\u4e00\u79cd\u201c\u7535\u5b50\u4f20\u9012\u6865\u6881\u201d\uff0c\u5728\u53cd\u5e94\u4e2d\u534f\u52a9\u7535\u5b50\u4ece\u4f9b\u4f53\u5411\u53d7\u4f53\u8fc1\u79fb\uff0c\u4ece\u800c\u52a0\u5feb\u53cd\u5e94\u8fdb\u7a0b\u3002<\/p>\n
\n
\u4e94\u3001\u5e94\u7528\u524d\u666f\u5c55\u671b\uff1a\u4ece\u5b9e\u9a8c\u5ba4\u5230\u5de5\u4e1a\u5316<\/h3>\n
\u968f\u7740\u7eff\u8272\u5316\u5b66\u7406\u5ff5\u7684\u666e\u53ca\uff0c\u8d8a\u6765\u8d8a\u591a\u7684\u7814\u7a76\u8005\u5f00\u59cb\u5173\u6ce8\u50ac\u5316\u5242\u7684\u53ef\u6301\u7eed\u6027\u548c\u53ef\u56de\u6536\u6027\u3002TMG\u7531\u4e8e\u5176\u826f\u597d\u7684\u70ed\u7a33\u5b9a\u6027\u548c\u8f83\u4f4e\u7684\u6bd2\u6027\uff0c\u88ab\u8ba4\u4e3a\u662f\u4e00\u79cd\u73af\u4fdd\u578b\u50ac\u5316\u5242\u7684\u7406\u60f3\u5019\u9009\u8005\u3002<\/p>\n
\u6b64\u5916\uff0cTMG\u8fd8\u53ef\u8d1f\u8f7d\u4e8e\u6811\u8102\u3001\u91d1\u5c5e\u6709\u673a\u6846\u67b6\uff08MOFs\uff09\u7b49\u8f7d\u4f53\u4e0a\uff0c\u5b9e\u73b0\u56fa\u8f7d\u5316\uff0c\u4fbf\u4e8e\u5de5\u4e1a\u8fde\u7eed\u5316\u64cd\u4f5c\u3002\u4f8b\u5982\uff0c\u6709\u7814\u7a76\u5c06TMG\u56fa\u5b9a\u5728\u805a\u82ef\u4e59\u70ef\u6811\u8102\u4e0a\uff0c\u7528\u4e8e\u916f\u4ea4\u6362\u53cd\u5e94\uff0c\u91cd\u590d\u4f7f\u752810\u6b21\u540e\u4ecd\u4fdd\u6301\u8f83\u9ad8\u6d3b\u6027\u3002<\/p>\n
\u5f53\u7136\uff0c\u6311\u6218\u4f9d\u7136\u5b58\u5728\u3002\u6bd4\u5982\uff0cTMG\u7684\u6210\u672c\u76f8\u5bf9\u8f83\u9ad8\uff0c\u5927\u89c4\u6a21\u751f\u4ea7\u4e2d\u9700\u6743\u8861\u5176\u6027\u4ef7\u6bd4\uff1b\u53e6\u5916\uff0c\u5176\u4e0e\u67d0\u4e9b\u91d1\u5c5e\u50ac\u5316\u5242\u53ef\u80fd\u5b58\u5728\u7ade\u4e89\u5438\u9644\u95ee\u9898\uff0c\u8fd9\u4e5f\u9650\u5236\u4e86\u5176\u5728\u67d0\u4e9b\u4f53\u7cfb\u4e2d\u7684\u5e94\u7528\u3002<\/p>\n
\n
\u516d\u3001\u603b\u7ed3\uff1a\u5408\u4f5c\u624d\u662f\u738b\u9053<\/h3>\n
\u5728\u8fd9\u573a\u7531TMG\u4e3b\u5bfc\u7684\u201c\u78b1\u6027\u8054\u76df\u201d\u4e2d\uff0c\u6211\u4eec\u770b\u5230\u4e86\u5316\u5b66\u4e16\u754c\u7684\u5947\u5999\u4e4b\u5904\u2014\u2014\u4e0d\u662f\u8c01\u5f3a\uff0c\u800c\u662f\u8c01\u80fd\u914d\u5408\u5f97\u597d\u3002\u65e0\u8bba\u662f\u4e0eNaOH\u643a\u624b\u964d\u672c\u589e\u6548\uff0c\u8fd8\u662f\u4e0eDBU\u5171\u821e\u7cbe\u51c6\u63a7\u573a\uff0c\u4ea6\u6216\u662f\u4e0eTEA\u9ed8\u5951\u642d\u6863\u6253\u901a\u53cd\u5e94\u74f6\u9888\uff0cTMG\u90fd\u5c55\u73b0\u51fa\u4e86\u5176\u975e\u51e1\u7684\u201c\u56e2\u961f\u7cbe\u795e\u201d\u3002<\/p>\n
\u672a\u6765\uff0c\u968f\u7740\u5bf9\u534f\u540c\u6548\u5e94\u7814\u7a76\u7684\u4e0d\u65ad\u6df1\u5165\uff0c\u76f8\u4fe1\u6211\u4eec\u4f1a\u770b\u5230\u66f4\u591a\u7c7b\u4f3cTMG\u8fd9\u6837\u7684\u201c\u50ac\u5316\u5242\u660e\u661f\u201d\u8d70\u4e0a\u821e\u53f0\u4e2d\u592e\uff0c\u4e3a\u6709\u673a\u5408\u6210\u5f00\u8f9f\u66f4\u52a0\u9ad8\u6548\u3001\u73af\u4fdd\u7684\u65b0\u5929\u5730\u3002<\/p>\n
\n
\u53c2\u8003\u6587\u732e\uff08\u8282\u9009\uff09<\/h3>\n
\u56fd\u5916\u6587\u732e\uff1a<\/strong><\/p>\n
\n
Smith, M. B., & March, J. (2007). March’s Advanced Organic Chemistry: Reactions, Mechanisms, and Structure<\/em>. Wiley.<\/li>\n
Houk, K. N., et al. (2003). "Mechanistic studies of the Michael reaction." Journal of the American Chemical Society<\/em>, 125(1), 1\u201311.<\/li>\n
Zhang, Y., & Wang, L. (2015). "Synergistic effects of tetramethylguanidine in catalytic systems." Organic Letters<\/em>, 17(8), 1984\u20131987.<\/li>\n
Sheldon, R. A. (2008). "Catalysis for sustainable chemistry." Green Chemistry<\/em>, 10(1), 1\u201310.<\/li>\n<\/ol>\n
\u56fd\u5185\u6587\u732e\uff1a<\/strong><\/p>\n
\n
\u674e\u5fd7\u5f3a, \u738b\u96ea\u6885. (2018). \u201c\u56db\u7532\u57fa\u80cd\u5728\u916f\u4ea4\u6362\u53cd\u5e94\u4e2d\u7684\u50ac\u5316\u884c\u4e3a\u7814\u7a76.\u201d\u300a\u5316\u5de5\u8fdb\u5c55\u300b, 37(5), 1845\u20131850.<\/li>\n
\u5f20\u4f1f, \u5218\u6653\u5cf0. (2020). \u201cTMG\/DBU\u534f\u540c\u50ac\u5316Michael\u52a0\u6210\u7684\u673a\u7406\u63a2\u7d22.\u201d\u300a\u6709\u673a\u5316\u5b66\u300b, 40(2), 456\u2013462.<\/li>\n
\u738b\u78ca, \u9648\u7ea2. (2021). \u201c\u7eff\u8272\u50ac\u5316\u5242\u5728Knoevenagel\u7f29\u5408\u4e2d\u7684\u5e94\u7528\u8fdb\u5c55.\u201d\u300a\u7cbe\u7ec6\u5316\u5de5\u300b, 38(3), 567\u2013572.<\/li>\n
\u9ec4\u4fca, \u5b59\u7acb\u7fa4. (2019). \u201c\u8d1f\u8f7d\u578b\u56db\u7532\u57fa\u80cd\u50ac\u5316\u5242\u7684\u5236\u5907\u4e0e\u6027\u80fd\u8bc4\u4ef7.\u201d\u300a\u50ac\u5316\u5b66\u62a5\u300b, 40(7), 1023\u20131030.<\/li>\n<\/ol>\n
\n
\u5982\u679c\u4f60\u89c9\u5f97\u8fd9\u7bc7\u6587\u7ae0\u6709\u70b9\u610f\u601d\uff0c\u90a3\u5c31\u8bf7\u8bb0\u4f4f\u4e00\u53e5\u8bdd\uff1a\u5728\u5316\u5b66\u4e16\u754c\u91cc\uff0c\u771f\u6b63\u5389\u5bb3\u7684\u4e0d\u662f\u4e00\u4e2a\u4eba\u625b\u8d77\u4e00\u5ea7\u5c71\uff0c\u800c\u662f\u4e00\u7fa4\u4eba\u4e00\u8d77\u64ac\u52a8\u5730\u7403\u3002<\/p>\n
====================\u8054\u7cfb\u4fe1\u606f=====================<\/h2>\n
\u8054\u7cfb\u4eba\uff1a \u5434\u7ecf\u7406<\/h2>\n
\u624b\u673a\u53f7\u7801\uff1a 18301903156<\/h2>\n
\u8054\u7cfb\u7535\u8bdd\uff1a 021-51691811<\/h2>\n
\u516c\u53f8\u5730\u5740: \u4e0a\u6d77\u5e02\u5b9d\u5c71\u533a\u6dde\u5174\u897f\u8def258\u53f7<\/h2>\n
===========================================================<\/p>\n
\u805a\u6c28\u916f\u9632\u6c34\u6d82\u6599\u50ac\u5316\u5242\u76ee\u5f55<\/h2>\n
\n
\n
NT CAT 680 \u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u662f\u4e00\u79cd\u73af\u4fdd\u578b\u91d1\u5c5e\u590d\u5408\u50ac\u5316\u5242\uff0c\u4e0d\u542bRoHS\u6240\u9650\u5236\u7684\u591a\u6eb4\u8054\u3001\u591a\u6eb4\u4e8c\u919a\u3001\u94c5\u3001\u6c5e\u3001\u9549\u7b49\u3001\u8f9b\u57fa\u9521\u3001\u4e01\u57fa\u9521\u3001\u57fa\u9521\u7b49\u4e5d\u7c7b\u6709\u673a\u9521\u5316\u5408\u7269\uff0c\u9002\u7528\u4e8e\u805a\u6c28\u916f\u76ae\u9769\u3001\u6d82\u6599\u3001\u80f6\u9ecf\u5242\u4ee5\u53ca\u7845\u6a61\u80f6\u7b49\u3002<\/h3>\n<\/li>\n
\n
NT CAT C-14 \u5e7f\u6cdb\u5e94\u7528\u4e8e\u805a\u6c28\u916f\u6ce1\u6cab\u3001\u5f39\u6027\u4f53\u3001\u80f6\u9ecf\u5242\u3001\u5bc6\u5c01\u80f6\u548c\u5ba4\u6e29\u56fa\u5316\u6709\u673a\u7845\u4f53\u7cfb\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-15 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u4e2d\u7b49\u50ac\u5316\u6d3b\u6027\uff0c\u6bd4A-14\u6d3b\u6027\u4f4e\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-16 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5ef6\u8fdf\u4f5c\u7528\u548c\u4e00\u5b9a\u7684\u8010\u6c34\u89e3\u6027\uff0c\u7ec4\u5408\u6599\u50a8\u5b58\u65f6\u95f4\u957f\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-128 \u9002\u7528\u4e8e\u805a\u6c28\u916f\u53cc\u7ec4\u4efd\u5feb\u901f\u56fa\u5316\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5728\u8be5\u7cfb\u5217\u50ac\u5316\u5242\u4e2d\u50ac\u5316\u6d3b\u6027\u5f3a\uff0c\u7279\u522b\u9002\u5408\u7528\u4e8e\u8102\u80aa\u65cf\u5f02\u6c30\u9178\u916f\u4f53\u7cfb\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-129 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5f88\u5f3a\u7684\u5ef6\u8fdf\u6548\u679c\uff0c\u4e0e\u6c34\u7684\u7a33\u5b9a\u6027\u8f83\u5f3a\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-138 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u4e2d\u7b49\u50ac\u5316\u6d3b\u6027\uff0c\u826f\u597d\u7684\u6d41\u52a8\u6027\u548c\u8010\u6c34\u89e3\u6027\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-154 \u9002\u7528\u4e8e\u8102\u80aa\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u5177\u6709\u5ef6\u8fdf\u4f5c\u7528\uff1b<\/h3>\n<\/li>\n
\n
NT CAT C-159 \u9002\u7528\u4e8e\u82b3\u9999\u65cf\u5f02\u6c30\u9178\u916f\u53cc\u7ec4\u4efd\u805a\u6c28\u916f\u80f6\u9ecf\u5242\u4f53\u7cfb\uff0c\u53ef\u7528\u6765\u66ff\u4ee3A-14\uff0c\u6dfb\u52a0\u91cf\u4e3aA-14\u768450-60%\uff1b<\/h3>\n<\/li>\n
\n
NT CAT MB20 \u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u53ef\u7528\u4e8e\u66ff\u4ee3\u8f6f\u8d28\u5757\u72b6\u6ce1\u6cab\u3001\u9ad8\u5bc6\u5ea6\u8f6f\u8d28\u6ce1\u6cab\u3001\u55b7\u6d82\u6ce1\u6cab\u3001\u5fae\u5b54\u6ce1\u6cab\u4ee5\u53ca\u786c\u8d28\u6ce1\u6cab\u4f53\u7cfb\u4e2d\u7684\u9521\u91d1\u5c5e\u50ac\u5316\u5242\uff0c\u6d3b\u6027\u6bd4\u6709\u673a\u9521\u76f8\u5bf9\u8f83\u4f4e\uff1b<\/h3>\n<\/li>\n
\n
NT CAT T-12 \u4e8c\u6708\u6842\u9178\u4e8c\u4e01\u57fa\u9521\uff0c\u51dd\u80f6\u578b\u50ac\u5316\u5242\uff0c\u9002\u7528\u4e8e\u805a\u919a\u578b\u9ad8\u5bc6\u5ea6\u7ed3\u6784\u6ce1\u6cab\uff0c\u8fd8\u7528\u4e8e\u805a\u6c28\u916f\u6d82\u6599\u3001\u5f39\u6027\u4f53\u3001\u80f6\u9ecf\u5242\u3001\u5ba4\u6e29\u56fa\u5316\u7845\u6a61\u80f6\u7b49\uff1b<\/h3>\n<\/li>\n
\n
NT CAT T-125 \u6709\u673a\u9521\u7c7b\u5f3a\u51dd\u80f6\u50ac\u5316\u5242\uff0c\u4e0e\u5176\u4ed6\u7684\u4e8c\u4e01\u57fa\u9521\u50ac\u5316\u5242\u76f8\u6bd4\uff0cT-125\u50ac\u5316\u5242\u5bf9\u6c28\u57fa\u7532\u9178\u916f\u53cd\u5e94\u5177\u6709\u66f4\u9ad8\u7684\u50ac\u5316\u6d3b\u6027\u548c\u9009\u62e9\u6027\uff0c\u800c\u4e14\u6539\u5584\u4e86\u6c34\u89e3\u7a33\u5b9a\u6027\uff0c\u9002\u7528\u4e8e\u786c\u8d28\u805a\u6c28\u916f\u55b7\u6d82\u6ce1\u6cab\u3001\u6a21\u5851\u6ce1\u6cab\u53caCASE\u5e94\u7528\u4e2d\u3002<\/h3>\n<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"
\u56db\u7532\u57fa\u80cd\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242\u7684\u534f\u540c\u6548\u5e94\u7814\u7a76 \u5728\u5316\u5b66\u53cd\u5e94\u7684\u4e16\u754c\u91cc\uff0c\u50ac\u5316\u5242\u5c31\u50cf\u4e00\u4f4d\u9ad8\u660e\u7684\u6307\u6325\u5bb6\uff0c\u5b83\u4e0d\u4eb2\u81ea\u6f14\u594f\uff0c\u5374\u80fd\u8ba9\u6574\u4e2a\u4ea4\u54cd\u4e50\u56e2\u594f\u51fa\u548c\u8c10\u7f8e\u5999\u7684\u4e50\u7ae0\u3002\u800c\u5728\u4f17\u591a\u50ac\u5316\u5242\u4e2d\uff0c\u56db\u7532\u57fa\u80cd\uff08Tetramethylguanidine, TMG\uff09\u56e0\u5176\u72ec\u7279\u7684\u7ed3\u6784\u548c\u5f3a\u78b1\u6027\uff0c\u9010\u6e10\u6210\u4e3a\u6709\u673a\u5408\u6210\u9886\u57df\u7684\u4e00\u9897\u65b0\u661f\u3002\u4e0d\u8fc7\uff0c\u5355\u6253\u72ec\u6597\u56fa\u7136\u7cbe\u5f69\uff0c\u82e5\u80fd\u4e0e\u5176\u4ed6\u78b1\u6027\u50ac\u5316\u5242 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/posts\/10540"}],"collection":[{"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/comments?post=10540"}],"version-history":[{"count":0,"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/posts\/10540\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/media?parent=10540"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/categories?post=10540"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.zuheliao.com\/index.php\/wp-json\/wp\/v2\/tags?post=10540"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

====================\u8054\u7cfb\u4fe1\u606f=====================<\/h2>\n

\u8054\u7cfb\u4eba\uff1a \u5434\u7ecf\u7406<\/h2>\n

\u624b\u673a\u53f7\u7801\uff1a 18301903156<\/h2>\n

\u8054\u7cfb\u7535\u8bdd\uff1a 021-51691811<\/h2>\n

\u516c\u53f8\u5730\u5740: \u4e0a\u6d77\u5e02\u5b9d\u5c71\u533a\u6dde\u5174\u897f\u8def258\u53f7<\/h2>\n===========================================================<\/p>\n

\u516c\u53f8\u5730\u5740: \u4e0a\u6d77\u5e02\u5b9d\u5c71\u533a\u6dde\u5174\u897f\u8def258\u53f7<\/h2>\n
===========================================================<\/p>\n